PUBLICATIONS
Independent Work (@ Baylor):
ZrH-Catalyzed Semi-Reduction of Esters Enabled by an Imine/Enamine Trap, Rebecca A. Kehner, Liela Bayeh-Romero, Under Review
ChemRxiv 10.26434/chemrxiv-2024-wq0q6
Mild Divergent Semi-Reductive Transformations of Secondary and Tertiary Amides via Zirconocene Hydride Catalysis, Rebecca A. Kehner, Ge Zhang, Liela Bayeh-Romero, JACS, 2023, 145, 4921.
Chemrxiv 10.26434/chemrxiv-2022-3tdb7
Organic Chemistry Portal Synopsis
Selective Zirconocene Hydride-Catalyzed Semi-Hydrogenation of Terminal Alkynes, Rebecca A. Kehner, Alexandra E. Lubaev, Manjula D. Rathnayake, Ryan Loden, Ge Zhang, Liela Bayeh-Romero, Tetrahedron, 2023, 133, 133267.
*** Special issue in honor of Prof. John Wood for his many years of service as associate Editor of TL.
Catalytic Chemo–, Regio–, Diastereo– and Enantioselective Bromochlorination of Unsaturated Systems Enabled by Lewis Base-Controlled Chloride Release, Alexandra E. Lubaev, Manjula D. Rathnayake, Favour Eze, Liela Bayeh-Romero, JACS, 2022, 144, 13294
Expanding Zirconocene Hydride Catalysis: In Situ Generation and Turnover of ZrH Catalysts Enabling Catalytic Carbonyl Reductions, Rebecca A. Kehner, Matthew Christian Hewitt, Liela Bayeh-Romero, ACS Catal., 2022, 12, 1758–1763
Prior Mentored Work:
Copper Hydride-Catalyzed Enantioselective Synthesis of Axially Chiral 1,3-Disubstituted Allenes, Liela Bayeh-Romero and Stephen L. Buchwald, J. Am. Chem. Soc. 2019, 141, 13788–13794
Enantioselective, Diastereoselective, and Regioselective Allylic Oxidation of Internal Olefins, Liela Bayeh, Phong Q. Le and Uttam K Tambar, Nature, 2017, 547, 196–200
Catalytic Asymmetric Intermolecular Allylic Functionalization of Unactivated Internal Alkenes, Liela Bayeh and Uttam K. Tambar, ACS Catal., 2017, 7, 8533–8543
A New Paradigm for GERD Pathogenesis. Not Acid Injury, but Cytokine-Mediated Inflammation Driven by HIF-2α: a Potential Role for Targeting HIF-2α to Prevent and Treat Reflux Esophagitis, Rhonda F. Souza, Liela Bayeh, Stuart J. Spechler, Uttam K. Tambar and Richard K. Bruick, Curr. Opin. Pharmacol., 2017, 37, 93–99
Regioselective and Diastereoselective Aminoarylation of 1,3-Dienes, Hongli Bao, Liela Bayeh, and Uttam K. Tambar, Chem. Sci., 2014, 5, 4863–4867
Isoform-Selective and Stereoselective Inhibition of Hypoxia Inducible Factor-2, Scheuermann, Thomas; Stroud, Daniel; Sleet, Christopher; Bayeh, Liela; Shokri, Cameron; Wang, Hanzhi; Caldwell, Charles; Longgood, Jamie; MacMillan, John; Bruick, Richard; Gardner, Kevin; Tambar, Uttam, J. Med. Chem., 2015, 58, 5930−5941
Bis(Phenylsulfonyl)sulfur Diimide, Liela Bayeh and Uttam K. Tambar, In Encyclopedia of Reagents for Organic Synthesis, Paquette, L., Ed.; John Wiley & Sons Ltd., DOI: 10.1002/047084289X.rn01764
Allylic Functionalization of Unactivated Olefins with Grignard Reagents, Hongli Bao, Liela Bayeh, and Uttam K. Tambar, Angew. Chem. Int. Ed., 2014, 53, 1664–1668
Catalytic Enantioselective Allylic Amination of Olefins for the Synthesis of ent-Sitagliptin, Hongli Bao, Liela Bayeh, and Uttam K. Tambar, Synlett, 2013, 24, 2459–2463
Development of Inhibitors of the PAS‐B Domain of the HIF-2α Transcription Factor, Jamie L. Rogers,* Liela Bayeh,* Thomas H. Scheuermann,* Jamie Longgood, Jason Key, Jacinth Naidoo, Lisa Melito, Cameron Shokri, Doug E. Frantz, Richard K. Bruick, Kevin H. Gardner, John B. MacMillan, and Uttam K. Tambar, J. Med. Chem., 2013, 56, 1739–1747
* These authors made equal contributions to the paper
Small-Molecule Inhibitors of Cathepsin L Incorporating Functionalized Ring-Fused Molecular Frameworks, Jiangli Song, Lindsay M. Jones, Gustavo E. Chavarria, Amanda K. Charlton-Sevcik, Adam Jantz, Audra Johansen, Liela Bayeh, Victoria Soeung, Lindsey K. Snyder, Shawn D. Lade Jr., David J. Chaplin, Mary Lynn Trawick, and Kevin G. Pinney, Bioorg. Med. Chem. Lett., 2013, 23, 2801–2807
Synthesis and Biochemical Evaluation of Thiochromanone Thiosemicarbazone Analogues as Inhibitors of Cathepsin L, Jiangli Song, Lindsay M. Jones, G. D. Kishore Kumar, Elizabeth S. Conner, Liela Bayeh, Gustavo E. Chavarria, Amanda K. Charlton-Sevcik, Shen-En Chen, David J. Chaplin, Mary Lynn Trawick, and Kevin G. Pinney, ACS Med. Chem. Lett., 2012, 3, 450–453